bioselБиотехнология и селекция растенийPlant Biotechnology and Breeding2658-62662658-6258VIR10.30901/2658-6266-2022-1-o4biosel-150Research ArticleКРАТКИЕ СООБЩЕНИЯBRIEF COMMUNICATIONSБиоинформатика прирастает Сибирью: к юбилею академика РАН Николая Александровича КолчановаBioinformatics benefits from Siberia: on the anniversary of Nikolay Aleksandrovich Kolchanov, Academician of the Russian Academy of Sciences (RAS)https://orcid.org/0000-0002-8470-8254ХлесткинаЕ. К.KhlestkinaE. K.

Елена Константиновна Хлесткина

доктор биологических наук, профессор РАН, директор, ВИР, 190000 Россия, Санкт-Петербург, ул. Б. Морская, 42, 44; член Президиума ЦС, ВОГиС, 196608 Россия, Санкт-Петербург, Пушкин 8, ш. Подбельского, д. 3

Elena K. Khlestkina

Dr. Sci. (Biology), Professor of the RAS, Director, VIR, 42, 44 Bolshaya Morskaya Street, St. Petersburg 190000, Russia; member of the Presidium, VOGiS, 3, Podbelsky highway, Pushkin, Saint-Petersburg 196608, Russia

director@vir.nw.ruhttps://orcid.org/0000-0002-8338-3494НижниковА. А.NizhnikovA. A.

Антон Александрович Нижников

доктор биологических наук, заведующий лабораторией №7 Протеомики надорганизменных систем, ВНИИСХМ, 196608 Россия, Санкт-Петербург, Пушкин 8, ш. Подбельского, д. 3; доцент, СПбГУ, 199034 Россия, Санкт-Петербург, Университетская наб., 7/9; ученый секретарь, ВОГиС, 196608 Россия, Санкт-Петербург, Пушкин 8, ш. Подбельского, д. 3

Anton A. Nizhnikov

Dr. Sci. (Biology), Head of Laboratory for Proteomics of Supra-Organismal Systems, ARRIAM, 3, Podbelsky highway, Pushkin, Saint-Petersburg 196608, Russia; Associate Professor, SPbU, 7/9, Universitetskaya embankment, Saint-Petersburg 199034, Russia; Scientific Secretary, VOGiS, 3, Podbelsky highway, Pushkin, Saint-Petersburg 196608, Russia

a.nizhnikov@arriam.ruhttps://orcid.org/0000-0001-8968-854XТихоновичИ. А.TikhonovichI. A.

Игорь Анатольевич Тихонович

доктор биологических наук, академик РАН, профессор, декан биологического факультета, СПбГУ, 199034 Россия, Санкт-Петербург, Университетская наб., 7/9; научный руководитель, ВНИИСХМ, 196608 Россия, Санкт-Петербург, Пушкин 8, ш. Подбельского, д. 3; президент ВОГиС, 196608 Россия, Санкт-Петербург, Пушкин 8, ш. Подбельского, д. 3

Igor A. Tikhonovich

Dr. Sci. (Biology), Academician of the Russian Academy of Sciences, Professor, Dean of the Faculty of Biology, SPbU, 7/9, Universitetskaya embankment, Saint-Petersburg 199034, Russia; Scientific Director, ARRIAM, 3, Podbelsky highway, Pushkin, Saint-Petersburg 196608, Russia; President of VOGiS, 3, Podbelsky highway, Pushkin, Saint-Petersburg 196608, Russia

igor.tikhonovich49@mail.ruФедеральный исследовательский центр Всероссийский институт генетических ресурсов растений имени Н.И. Вавилова, Вавиловское общество генетиков и селекционеровN.I. Vavilov All-Russian Institute of Plant Genetic Resources,Всероссийский научно-исследовательский институт сельскохозяйственной микробиологии, Санкт-Петербургский государственный университет, Вавиловское общество генетиков и селекционеровAll-Russia Research Institute for Agricultural Microbiology, St. Petersburg State University, Vavilov Society of Geneticists and BreedersСанкт-Петербургский государственный университет, Всероссийский научно-исследовательский институт сельскохозяйственной микробиологии, Вавиловское общество генетиков и селекционеровSt. Petersburg State University, All-Russia Research Institute for Agricultural Microbiology, Vavilov Society of Geneticists and Breeders202205042022514751Copyright © Хлесткина Е.К., Нижников А.А., Тихонович И.А., 20222022Хлесткина Е.К., Нижников А.А., Тихонович И.А.Khlestkina E.K., Nizhnikov A.A., Tikhonovich I.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://biosel.elpub.ru/jour/article/view/150

9 января 2022 г. исполнилось 75 лет академику РАН, доктору биологических наук, научному руководителю Федерального исследовательского центра Институт цитологии и генетики Сибирского отделения Российской академии наук, первому вице-президенту Вавиловского общества генетиков и селекционеров профессору Николаю Александровичу Колчанову. Академик Н.А. Колчанов – выдающийся специалист в области биоинформатики и системной компьютерной биологии, под руководством которого сформировалась и получила общемировое развитие крупнейшая в этом направлении отечественная научная школа. Он является автором и соавтором около 700 публикаций в отечественной и зарубежной печати, 18 авторских свидетельств и 8 патентов. В течение почти 20 лет академик Н.А. Колчанов является заведующим и профессором кафедры информационной биологии факультета естественных наук Новосибирского государственного университета. Он подготовил 12 кандидатов наук и 2 докторов наук. Его ученики, работающие в ведущих отечественных и зарубежных научных центрах, являются гордостью российской науки и вносят весомый вклад в мировой уровень развития современной биоинформатики.

January 9, 2022 marks the 75th anniversary of Nikolai Aleksandrovich Kolchanov, Doctor of Biological Sciences, Professor, Academician of the Russian Academy of Sciences, Scientific Leader of the Federal Research Center the Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences, First Vice-President of the Vavilov Society of Geneticists and Breeders. Acad. N.A. Kolchanov is a prominent specialist in the field of bioinformatics and systems computational biology, under whose guidance the largest domestic scientific school in this area has formed and received global development. He is the author and co-author of about 700 publications in domestic and foreign press, holder of 18 copyright certificates and 8 patents. For almost 20 years, Acad. Kolchanov is the Head and Professor of the Department of Information Biology with the Faculty of Natural Sciences of Novosibirsk State University. He supervised the work of 12 doctoral and 2 senior doctorate students. His students, who work in leading domestic and foreign scientific centers, are the pride of Russian science and make a significant contribution to the world level of development of modern bioinformatics at the global level.

BGRSбиоинформатикагенные сетиинформационная биологиямолекулярно-генетические системысистемная биология растенийBGRSbioinformaticsgene networksmolecular-genetic systemsplant systems biologyReferencesAnanko E.A., Podkolodny N.L., Stepanenko I.L., Ignatieva E.V., Podkolodnaya O.A., Kolchanov N.A. GeneNet: a database on structure and functional organisation of gene networks. Nucleic Acids Research. 2002;30(1):398-401. DOI: 10.1093/nar/30.1.398Ananko E.A., Podkolodny N.L., Stepanenko I.L., Ignatieva E.V., Podkolodnaya O.A., Kolchanov N.A. GeneNet: a database on structure and functional organisation of gene networks. Nucleic Acids Research. 2002;30(1):398-401. DOI: 10.1093/nar/30.1.398Bragina E.Yu., Tiys E.S., Freidin M.B., Koneva L.A., Demenkov P.S., Ivanisenko V.A., Kolchanov N.A., Puzyrev V.P. Insights into pathophysiology of dystropy through the analysis of gene networks: an example of bronchial asthma and tuberculosis. Immunogenetics. 2014;66(7-8):457-465. DOI: 10.1007/s00251-014-0786-1Bragina E.Yu., Tiys E.S., Freidin M.B., Koneva L.A., Demenkov P.S., Ivanisenko V.A., Kolchanov N.A., Puzyrev V.P. Insights into pathophysiology of dystropy through the analysis of gene networks: an example of bronchial asthma and tuberculosis. Immunogenetics. 2014;66(7-8):457-465. DOI: 10.1007/s00251-014-0786-1Кафедра информационной биологии, Новосибирский Государственный Университет: [сайт]. URL: https://kib.nsu.ru/ [дата обращения: 28.11.2021].Department of Information Biology, Novosibirsk State University (Kafedra Informatsionnoy Biologii. Novosibirskii Gosudarstvennyi Universitet) [website]. [in Russian]. URL: https://kib.nsu.ru/ [дата обращения: 28.11.2021].Heinemeyer T., Wingender E., Reuter I., Hermjakob H., Kel A.E., Kel O.V., Ignatieva E.V., Ananko E.A., Podkolodnaya O.A., Kolpakov F.A., Podkolodny N.L., Kolchanov N.A. Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL. Nucleic Acids Research. 1998;26(1):362-367. DOI: 10.1093/nar/26.1.362Heinemeyer T., Wingender E., Reuter I., Hermjakob H., Kel A.E., Kel O.V., Ignatieva E.V., Ananko E.A., Podkolodnaya O.A., Kolpakov F.A., Podkolodny N.L., Kolchanov N.A. Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL. Nucleic Acids Research. 1998;26(1):362-367. DOI: 10.1093/nar/26.1.362Ivanisenko V.A., Pintus S.S., Grigorovich D.A., Kolchanov N.A. PDBSite: a database of the 3D structure of protein functional sites. Nucleic Acids Research. 2005;33 Suppl 1:D183-D187. DOI: 10.1093/nar/gki105Ivanisenko V.A., Pintus S.S., Grigorovich D.A., Kolchanov N.A. PDBSite: a database of the 3D structure of protein functional sites. Nucleic Acids Research. 2005;33 Suppl 1:D183-D187. DOI: 10.1093/nar/gki105Ivanisenko V.A., Pintus S.S., Grigorovich D.A., Kolchanov N.A. PDBSiteScan: a program for searching for active, binding and posttranslational modification sites in the 3D structures of proteins. Nucleic Acids Research. 2004;32 Suppl 2:W549-W554. DOI: 10.1093/nar/gkh439Ivanisenko V.A., Pintus S.S., Grigorovich D.A., Kolchanov N.A. PDBSiteScan: a program for searching for active, binding and posttranslational modification sites in the 3D structures of proteins. Nucleic Acids Research. 2004;32 Suppl 2:W549-W554. DOI: 10.1093/nar/gkh439Kel-Margoulis O.V., Romashchenko A.G., Kolchanov N.A., Wingender E., Kel A.E. COMPEL: a database on composite regulatory elements providing combinatorial transcriptional regulation. Nucleic Acids Research. 2000;28(1):311-315. DOI: 10.1093/nar/28.1.311Kel-Margoulis O.V., Romashchenko A.G., Kolchanov N.A., Wingender E., Kel A.E. COMPEL: a database on composite regulatory elements providing combinatorial transcriptional regulation. Nucleic Acids Research. 2000;28(1):311-315. DOI: 10.1093/nar/28.1.311Kolchanov N.A., Ananko E.A., Podkolodnaya O.A., Ignatieva E.V., Stepanenko I.L., Kel-Margoulis O.V., Kel A.E., Merkulova T.I., Goryachkovskaya T.N., Busygina T.V., Kolpakov F.A., Podkolodny N.L., Naumochkin A.N., Romashchenko A.G. Transcription Regulatory Regions Database (TRRD): its status in 1999. Nucleic Acids Research. 1999;27(1):303-306. DOI: 10.1093/nar/27.1.303Kolchanov N.A., Ananko E.A., Podkolodnaya O.A., Ignatieva E.V., Stepanenko I.L., Kel-Margoulis O.V., Kel A.E., Merkulova T.I., Goryachkovskaya T.N., Busygina T.V., Kolpakov F.A., Podkolodny N.L., Naumochkin A.N., Romashchenko A.G. Transcription Regulatory Regions Database (TRRD): its status in 1999. Nucleic Acids Research. 1999;27(1):303-306. DOI: 10.1093/nar/27.1.303Kolchanov N.A., Ignatieva E.V., Ananko E.A., Podkolodnaya O.A., Stepanenko I.L., Merkulova T.I., Pozdnyakov M.A., Podkolodny N.L., Naumochkin A.N., Romashchenko A.G. Transcription Regulatory Regions Database (TRRD): its status in 2002. Nucleic Acids Research. 2002;30(1):312-317. DOI: 10.1093/nar/30.1.312Kolchanov N.A., Ignatieva E.V., Ananko E.A., Podkolodnaya O.A., Stepanenko I.L., Merkulova T.I., Pozdnyakov M.A., Podkolodny N.L., Naumochkin A.N., Romashchenko A.G. Transcription Regulatory Regions Database (TRRD): its status in 2002. Nucleic Acids Research. 2002;30(1):312-317. DOI: 10.1093/nar/30.1.312Kolchanov N.A., Nedosekina E.A., Ananko E.A., Likhoshvai V.A., Podkolodny N.L., Ratushny A.V., Stepanenko I.L., Podkolodnaya O.A., Ignatieva E.V., Matushkin Y.G. GeneNet database: description and modeling of gene networks. Silico Biology. 2002a;2(2):97-110.Kolchanov N.A., Nedosekina E.A., Ananko E.A., Likhoshvai V.A., Podkolodny N.L., Ratushny A.V., Stepanenko I.L., Podkolodnaya O.A., Ignatieva E.V., Matushkin Y.G. GeneNet database: description and modeling of gene networks. Silico Biology. 2002a;2(2):97-110.KolchanovN.A., Podkolodnaya O.A., Ananko E.A., Ignatieva E.V., Stepanenko I.L., Kel-Margoulis O.V., Kel A.E., Merkulova T.I., Goryachkovskaya T.N., Busygina T.V., Kolpakov F.A., Podkolodny N.L., Naumochkin A.N., Korostishevskaya I.M., Romashchenko A.G., Overton G.C. Transcription Regulatory Regions Database (TRRD): its status in 2000. Nucleic Acids Research. 2000;28(1):298-301. DOI: 10.1093/nar/28.1.298KolchanovN.A., Podkolodnaya O.A., Ananko E.A., Ignatieva E.V., Stepanenko I.L., Kel-Margoulis O.V., Kel A.E., Merkulova T.I., Goryachkovskaya T.N., Busygina T.V., Kolpakov F.A., Podkolodny N.L., Naumochkin A.N., Korostishevskaya I.M., Romashchenko A.G., Overton G.C. Transcription Regulatory Regions Database (TRRD): its status in 2000. Nucleic Acids Research. 2000;28(1):298-301. DOI: 10.1093/nar/28.1.298Kolpakov F.A., Ananko E.A., Kolesov G.B., Kolchanov N.A. GeneNet: a gene network database and its automated visualization. Bioinformatics. 1998;14(6):529-537. DOI: 10.1093/bioinformatics/14.6.529Kolpakov F.A., Ananko E.A., Kolesov G.B., Kolchanov N.A. GeneNet: a gene network database and its automated visualization. Bioinformatics. 1998;14(6):529-537. DOI: 10.1093/bioinformatics/14.6.529Mironova V.V., Omelyanchuk N.A., Novoselova E.S., Doroshkov A.V., Kazantsev F.V., Kochetov A.V., Kolchanov N.A., Mjolsness E., Likhoshvai V.A. Combined in silico/in vivo analysis of mechanisms providing for root apical meristem self-organization and maintenance. Annals of Botany. 2012;110(2):349-360. DOI: 10.1093/aob/mcs069Mironova V.V., Omelyanchuk N.A., Novoselova E.S., Doroshkov A.V., Kazantsev F.V., Kochetov A.V., Kolchanov N.A., Mjolsness E., Likhoshvai V.A. Combined in silico/in vivo analysis of mechanisms providing for root apical meristem self-organization and maintenance. Annals of Botany. 2012;110(2):349-360. DOI: 10.1093/aob/mcs069Mironova V.V., Omelyanchuk N.A., Yosiphon G., Fadeev S.I., Kolchanov N.A., Mjolsness E., Likhoshvai V.A. A plausible mechanism for auxin patterning along the developing root. BMC Systems Biology. 2010;4 Suppl 1:98. DOI: 10.1186/1752-0509-4-98Mironova V.V., Omelyanchuk N.A., Yosiphon G., Fadeev S.I., Kolchanov N.A., Mjolsness E., Likhoshvai V.A. A plausible mechanism for auxin patterning along the developing root. BMC Systems Biology. 2010;4 Suppl 1:98. DOI: 10.1186/1752-0509-4-98Omelyanchuk N.A., Wiebe D.S., Novikova D.D., Levitsky V.G., Klimova N., Gorelova V., Weinholdt C., Vasiliev G.V., Zemlyanskaya E.V., Kolchanov N.A., Kochetov A.V., Grosse I., Mironova V.V. Auxin regulates functional gene groups in a fold-change-specific manner in Arabidopsis thaliana roots. Scientific Reports. 2017;7(1):2489. DOI: 10.1038/s41598-017-02476-8Omelyanchuk N.A., Wiebe D.S., Novikova D.D., Levitsky V.G., Klimova N., Gorelova V., Weinholdt C., Vasiliev G.V., Zemlyanskaya E.V., Kolchanov N.A., Kochetov A.V., Grosse I., Mironova V.V. Auxin regulates functional gene groups in a fold-change-specific manner in Arabidopsis thaliana roots. Scientific Reports. 2017;7(1):2489. DOI: 10.1038/s41598-017-02476-8Podkolodnaya O.A., Yarkova E.E., Demenkov P.S., Konovalova O.S., Ivanisenko V.A., Kolchanov N.A. Application of the ANDCell computer system to reconstruction and analysis of associative networks describing potential relationships between myopia and glaucoma. Russian Journal of Genetics: Applied Research. 2011;1(1):21-28. DOI: 10.1134/S2079059711010059Podkolodnaya O.A., Yarkova E.E., Demenkov P.S., Konovalova O.S., Ivanisenko V.A., Kolchanov N.A. Application of the ANDCell computer system to reconstruction and analysis of associative networks describing potential relationships between myopia and glaucoma. Russian Journal of Genetics: Applied Research. 2011;1(1):21-28. DOI: 10.1134/S2079059711010059Rogozin I.B., Kolchanov N.A. Somatic hypermutagenesis in immunoglobulin genes: II. Influence of neighbouring base sequences on mutagenesis. Biochimica et Biophysica Acta (BBA) – Gene Structure and Expression. 1992;1171(1):11-18. DOI: 10.1016/0167-4781(92)90134-LRogozin I.B., Kolchanov N.A. Somatic hypermutagenesis in immunoglobulin genes: II. Influence of neighbouring base sequences on mutagenesis. Biochimica et Biophysica Acta (BBA) – Gene Structure and Expression. 1992;1171(1):11-18. DOI: 10.1016/0167-4781(92)90134-LРоссийская академия наук: [официальный портал]. URL: http://www.ras.ru [дата обращения: 29.11.2021].Russian Academy of Sciences (Rossiiskaya Akademiya Nauk) [official portal]. [in Russian]. URL: http://www.ras.ru [дата обращения: 29.11.2021].Shindyalov I.N., Kolchanov N.A., Sander C. Can three-dimensional contacts in protein structures be predicted by analysis of correlated mutations?. Protein Engineering, Design and Selection. 1994;7(3):349-358. DOI: 10.1093/protein/7.3.349Shindyalov I.N., Kolchanov N.A., Sander C. Can three-dimensional contacts in protein structures be predicted by analysis of correlated mutations?. Protein Engineering, Design and Selection. 1994;7(3):349-358. DOI: 10.1093/protein/7.3.349Федеральный исследовательский центр Институт цитологии и генетики Сибирского отделения Российской академии наук» (ИЦиГ СО РАН): [сайт]. URL: http://www.bionet.nsc.ru [дата обращения: 28.11.2021].The Federal Research Center Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences: [website]. [in Russian]. URL: http://www.bionet.nsc.ru [дата обращения: 28.11.2021].Wingender E., Kel A.E., Kel O.V., Karas H., Heinemeyer T., Dietze P., Knüppel R., Romaschenko A.G., Kolchanov N.A. TRANSFAC, TRRD and COMPEL: towards a federated database system on transcriptional regulation. Nucleic Acids Research. 1997;25(1):265-268. DOI: 10.1093/nar/25.1.265Wingender E., Kel A.E., Kel O.V., Karas H., Heinemeyer T., Dietze P., Knüppel R., Romaschenko A.G., Kolchanov N.A. TRANSFAC, TRRD and COMPEL: towards a federated database system on transcriptional regulation. Nucleic Acids Research. 1997;25(1):265-268. DOI: 10.1093/nar/25.1.265

The authors declare that there are no conflicts of interest present.